Product Overview - Medik8 Intelligent Retinol TR. Medik8 Intelligent Retinol TR is a performance-enhanced vitamin A night serum that represents the pinnacle of clinically-proven anti-ageing skincare. This advanced formulation combines pure Retinol with Climbazole, a breakthrough retinol-boosting ingredient, and Medik8's proprietary Time Release Technology to deliver visible youth-renewing results whilst maintaining exceptional skin comfort. Available in three progressive strengths to suit every level of vitamin A experience, this intelligent serum is expertly designed to work alongside your skin's natural nightly regenerative cycle.. The water-free, Squalane-infused formulation ensures optimal retinol stability and efficacy whilst nourishing the complexion with skin-identical lipids. Enhanced with Vitamin E for antioxidant protection, this professional-grade serum addresses concerns including fine lines, wrinkles, uneven texture, and loss of firmness. Suitable for all skin types, including sensitive skin, when phased in gradually following the recommended protocol.. Choose Your Strength. Intelligent Retinol TR is available in three progressive strengths, allowing you to tailor your vitamin A treatment to your experience level and skin tolerance. All formulations feature the same intelligent combination of climbazole enhancement, Time Release Technology, and nourishing squalane - the only difference is the retinol concentration.. Intelligent Retinol 3TR (0.3% Retinol). Best for: First-time retinol users, sensitive skin, or those upgrading from gentler vitamin A derivatives. This strength provides an effective yet gentle introduction to retinol, delivering visible anti-ageing results whilst minimising irritation potential. Ideal starting point for building vitamin A tolerance.. Intelligent Retinol 6TR (0.6% Retinol). Best for: Intermediate users who have successfully built tolerance with 3TR or have previous retinol experience. This mid-range strength offers enhanced anti-ageing power for more pronounced results whilst remaining comfortable for regular use. Perfect for progressing your vitamin A journey.. Intelligent Retinol 10TR (1% Retinol). Best for: Advanced vitamin A users seeking maximum anti-ageing efficacy. This highest strength delivers supercharged results for those with established retinol tolerance. Ideal for experienced users ready for the most powerful vitamin A treatment in the Intelligent Retinol range.. Our experts recommend: Start with 3TR regardless of your age or skin concerns. Once you've used an entire bottle comfortably at nightly frequency (approximately 2-3 months), you can progress to the next strength. This ladder approach ensures optimal results whilst maintaining skin comfort throughout your vitamin A journey.. Key Benefits at a Glance:. Immediate Benefits:. Gentle overnight delivery - Time Release Technology ensures retinol is gradually released throughout the night, minimising irritation whilst maximising visible results. Skin barrier support - Squalane, a skin-identical lipid, immediately nourishes and supports the natural barrier function. Antioxidant protection - Vitamin E provides immediate defence against environmental free radical damage. Lightweight absorption - Dry-touch serum formula sinks in rapidly without residue, allowing seamless layering with moisturiser. Enhanced comfort - Climbazole boosts retinol activity without increasing sensitivity potential, ensuring comfortable application from the start. Long-Term Benefits:. With consistent use over 4-6 weeks and beyond, Intelligent Retinol TR delivers transformative improvements to skin health. The formulation works to support collagen synthesis whilst preventing its breakdown, resulting in visibly plumper, firmer, and more youthful-looking skin. By enhancing the skin's natural exfoliation cycle, the serum promotes cellular renewal, revealing a smoother, more refined complexion with improved clarity and radiance.. The unique climbazole enhancement blocks the enzymes responsible for breaking down retinoic acid in the skin, creating a reservoir of active vitamin A that prolongs anti-ageing effects. This clinically-backed approach means users experience supercharged visible results - the power of higher retinol percentages without additional irritation. Fine lines and wrinkles are progressively softened, uneven pigmentation is visibly reduced, and overall skin texture becomes noticeably smoother and more even-toned.. How will it feel on my Skin?:. Intelligent Retinol TR features a silky, dry-touch texture that absorbs rapidly into the skin without leaving a greasy or heavy residue. The squalane-infused, oil-based serum glides effortlessly across the face, neck, and décolletage, providing instant nourishment whilst maintaining a lightweight feel. Users report waking to skin that feels noticeably softer, smoother, and more supple. The Time Release Technology ensures comfort throughout the night, with most users experiencing minimal to no irritation when following the recommended phase-in protocol. For specific texture guidance tailored to your skin type, speak to our experts for personalised application advice.. Who is it Suitable For?. All skin types including sensitive, dry, combination, and oily complexions. Those new to vitamin A seeking a gentle introduction (select Intelligent Retinol 3TR). Intermediate vitamin A users ready for enhanced results (select Intelligent Retinol 6TR). Advanced users seeking maximum anti-ageing power (select Intelligent Retinol 10TR). Individuals concerned with fine lines, wrinkles, and loss of firmness. Those addressing uneven skin tone, texture irregularities, and enlarged pores. Anyone seeking clinically-proven anti-ageing results with minimised irritation. Suitable for ages 25+ looking to prevent and address visible signs of ageing. Why choose Medik8 Intelligent Retinol TR?. Our experts recommend Intelligent Retinol TR for its unique combination of proven efficacy and exceptional tolerance. The innovative climbazole enhancement delivers supercharged anti-ageing results - clinically proven to boost retinol activity without increasing irritation potential. Combined with Medik8's proprietary Time Release Technology and a choice of three progressive strengths, this intelligent formulation allows you to build your vitamin A tolerance safely whilst achieving visible, transformative results. As part of Medik8's evidence-based CSA Philosophy, this professional-grade serum represents the gold standard in nighttime skin rejuvenation.